ー种含有环氧虫啉的杀虫组合物ー kinds of pesticidal compositions containing epoxy insect morpholino

技术领域 Technical Field

[0001] 本发明涉及ー种杀虫组合物，活性成分为第一活性成分环氧虫啉和第二活性成分选自拟除虫菊酯类杀虫剂联苯菊酯或高效氯氟氰菊酷，属于复配农药技术领域。 [0001] The present invention relates to pesticidal compositions ー, the active ingredient is an active ingredient of epoxy first worm and the second active ingredient is selected from morpholino pyrethroid insecticide bifenthrin or cyhalothrin chrysanthemum cool, belonging to the technical field of pesticide compound.

背景技术 Background

[0002] 环氧虫啉为新烟碱类杀虫剂，由武汉工程大学创制，化学名称:1-(2，3_环氧丙基)-N-硝基亚咪唑烷-2-基胺，化学分子式C6HltlN4Op对害虫有内吸、胃毒和触杀作用，可用于防治农作物上的同翅目害虫。 [0002] Epoxy insect morpholine as neonicotinoids, created by the Wuhan Institute of Technology, Chemical Name: 1- (2,3_ epoxy propyl) -N- nitromethylene imidazolidine-2-amine , chemical formula C6HltlN4Op uptake of pests, stomach poisoning and contact action, can be used to control Homoptera pests on crops. 作为ー种新烟碱类杀虫剂，环氧虫啉在使用过程中存在抗性风险，而与不同类型的杀虫剂合理混用，对于充分有效推广环氧虫啉，延长其使用寿命具有重要作用。 As ー kinds of neonicotinoid insecticides, epoxy insect resistance risk morpholino exist in the course, but with a reasonable mix of different types of pesticides, for the full and effective promotion of epoxy insect morpholine, extend the life of an important effect.

[0003]联苯菊酯，英文名称 bifenthrin ;FMC_54800 ；Biphenthrin ；Brigade ；Capture ；Talstar,别名氟氯菊酯；天王星；虫螨灵；毕芬宁；化学名称:2_甲基联苯基_3_基甲基-(Z) -(IRS)-顺-3-(2-氯-3, 3, 3- ニ氟-1-丙烯基)-2, 2- ニ甲基环丙烧羧酸酯，具有触杀、胃毒作用，无内吸、熏蒸作用，杀虫作用较迅速。 [0003] bifenthrin, the English name of bifenthrin; FMC_54800; Biphenthrin; Brigade; Capture; Talstar, alias bifenthrin; Uranus; carbofuran spirit; Bifen Ning; chemical name: 2_-methyl-biphenyl _3 _ methyl - (Z) - (IRS) - cis-3- (2-chloro-3, 3, 3-Ni-fluoro-1-propenyl) -2,2-ni methylcyclopropyl burn carboxylate , with tag, stomach poisoning, no uptake, fumigation, insecticidal effect more rapidly.

[0004] 高效氯氟氰菊酷，英文通用名:Lambda-cyhalothrin,化学名称:3- (2-氯-3，3, 3- ニ氟丙烯基)-2, 2- ニ甲基环丙烧羧酸a -氰基-3-苯氧苄基酯，杀虫谱广，活性较高，药效迅速，喷洒后耐雨水冲刷，但长期使用易对其产生抗性，对刺吸式ロ器的害虫及害螨有一定防效，但对螨的使用剂量要比常规用量増加I 一2倍。 [0004] cyhalothrin chrysanthemum cool, English common name: Lambda-cyhalothrin, Chemical Name: 3- (2-chloro-3,3, 3-fluoro-ni-propenyl) -2,2-ni methylcyclopropyl burn carboxylic acid a - cyano-3-phenoxybenzyl ester, broad spectrum, high activity, rapid efficacy, after spraying rain erosion resistance, but its long-term use is easy to become resistant to sucking ro unit and mite pests have necessarily effective, but the mites dose than conventional amounts to increase in I-2 times. 适用于花生、大豆、棉花、果树、蔬菜的害虫。 Suitable for peanuts, soybeans, cotton, fruit trees, vegetables pests.

[0005] 作为ー种新型新烟碱类杀虫剂，环氧虫啉在上市后存在着使用成本高，抗性风险逐渐増大的风险，对同翅目害虫高效，对鳞翅`目、半翅目害虫药效较差的缺陷；拟除虫菊酷类杀虫剂联苯菊酷、高效氯氟氰菊酯杀虫效果好，速效性快，但持效期短，逐年使用，抗性发展很快，发明人意外发现将环氧虫啉与联苯菊酯、高效氯氟氰菊酯混配使用，具有显著的增效效果，可降低使用成本，减缓害虫抗性的产生的作用。 [0005] As ー new type of neonicotinoid insecticides, insect morpholino epoxy exist after the listing of high cost, risk of resistance gradually Zeng big risk, Homoptera efficient `Head of the Lepidoptera, half Hymenoptera insects poor efficacy defects; pyrethroid insecticide Bifenthrin cool, cyhalothrin insecticidal effect is good, quick result fast, but short duration, yearly use, development of resistance to it fast, inventors have unexpectedly found that ethylene insect morpholine and bifenthrin, cyhalothrin mixed use, a significant synergistic effect, can reduce the cost, reduce the role of pest resistance generated.

发明内容 DISCLOSURE

[0006] 本发明的目的在于提供一种组分合理，显著增效，杀虫效果好，用药成本低的含有环氧虫啉的杀虫组合物。 [0006] The object of the present invention is to provide a reasonable component significant synergistic insecticidal effect, low drug costs pesticidal compositions containing epoxy insect morpholino.

[0007] 本发明的另ー目的在于提供上述杀虫组合物在防治农作物蚜虫、蝽象上的应用。 Another aim of the invention ー [0007] This provides control aphids, bugs like application on crops above insecticidal composition.

[0008] 为了克服现有单ー制剂的缺陷，本发明的技术方案是这样解决的: [0008] In order to overcome the deficiencies of the prior single ー formulation aspect of the present invention is solved:

ー种含有环氧虫啉的杀虫组合物，组合物活性成分为: Insecticidal composition comprising an epoxy ー species of insects morpholine, compositions containing the active ingredient:

(1)第一活性成分环氧虫啉； (1) a first active ingredient epoxy insects morpholine;

(2)第二活性成分联苯菊酯或高效氯氟氰菊酯； (2) a second active ingredient bifenthrin or lambda-cyhalothrin;

其中，第一活性成分与第二活性成分的重量比是1:10-20:1，优选为1:5-10:1，更优选为1:2-5:1，最优选为1:1-2:1。 Wherein the weight ratio of the first active ingredient and the second active ingredient is 1: 10-20: 1, preferably 1: 5-10: 1, more preferably from 1: 2-5: 1, most preferably 1: 1 -twenty one.

[0009] 第一活性成分与第二活性成分的含量之和为所述组合物总重量的3%-80%，优选为10% -70%O [0009] The content of the first active ingredient and the second active ingredient and a 3% -80% of the total weight of the composition, preferably 10% -70% O

[0010] 本发明按照本领域技术人员所公知的方法，可以配制的制剂剂型是水分散粒剂、可湿性粉剂、悬浮剂、乳油或微乳剂。 [0010] In accordance with the present invention, those skilled in the known methods, can be formulated Formulations are water dispersible granules, wettable powders, suspensions, creams or microemulsion.

[0011] 对于水分散粒剂来说，本领域技术人员很熟悉使用相应的助剂完成本发明。 [0011] For a water dispersible granules, the skilled person is familiar with the appropriate additives completed the present invention. 分散剂如聚羧酸盐类(TERSPERSE 2700、T36、GY-D06等)、木质素磺酸盐类(Ufoxane 3A、Borresperse NA、Borresperse CA-SA等)、拉开粉BX(ニ丁基萘磺酸钠)、萘和烷基萘甲醒缩合物磺酸盐类(NN0、MF、Morwet D_425、Tamol NN、TERSPERSE2020等)、EO-PO嵌段聚醚类、烷基酚聚氧こ烯基醚磷酸酯、烷基酚聚氧こ烯基醚甲醛缩合物硫酸盐(S0PA)，中ー种或多种；润湿剂如硫酸盐类(K-12)、磺酸盐类(ABS-Na、BX> Terwet 1004等)、复合润湿剂(MorwetEFff)中ー种或多种；崩解剂如硫酸铵、尿素、硫酸钠、聚こ烯吡咯烷酮、淀粉及其衍生物、膨润土等中ー种或多种；粘结剂如淀粉、葡萄糖、聚こ烯醇、聚こニ醇、羧甲基纤维素钠、蔗糖等中的ー种或多种；填料如硅藻土、高岭土、轻钙、滑石粉、白炭黑、凹凸棒土、陶土等ー种或多种。 Dispersants such as poly-carboxylic acid salt (TERSPERSE 2700, T36, GY-D06, etc.), lignin sulfonate (Ufoxane 3A, Borresperse NA, Borresperse CA-SA, etc.), opened powder BX (Ni-butyl naphthalene sulfonate sodium), naphthalene and alkyl naphthalene sulfonate condensate A wake (NN0, MF, Morwet D_425, Tamol NN, TERSPERSE2020 etc.), EO-PO block polyether, alkylphenol ether ko ene phosphate, polyoxyethylene alkylphenol ether formaldehyde condensate ko alkenyl sulfates (S0PA), in ー or more; wetting agents such as sulfates (K-12), sulfonates (ABS-Na, BX> Terwet 1004, etc.), composite wetting agent (MorwetEFff) in ー or more; disintegrating agents such as ammonium sulfate, urea, sodium sulfate, polyethylene ko polyvinylpyrrolidone, starch and its derivatives, bentonite, etc. ー species or variety; binders such as starch, glucose, polyethylene ko alcohol, polyethylene ko ni alcohol, sodium carboxymethyl cellulose, sucrose and the like ー or more; fillers such as diatomaceous earth, kaolin, light calcium, talc powder, silica, attapulgite clay and other ー or more.

[0012] 对可湿性粉剂，可使用的助剂有:分散剂如聚羧酸盐类(TERSPERSE 2700、T36、GY-D06 等)、木质素横酸盐类(Ufoxane 3A、Borresperse NA、Borresperse CA-SA 等)、萘和烷基萘甲醛缩合物磺酸盐类(NNO、MF、Morwet D-425、Tamol NN、TERSPERSE2020等)、拉开粉BX (ニ丁基萘磺酸钠)、EO-PO嵌段聚醚类、烷基酚聚氧こ烯基醚磷酸酯、烷基酚聚氧こ烯基醚甲醛缩合物硫酸盐(S0PA)，中ー种或多种；润湿剂如硫酸盐类(K-12)、磺酸盐类(ABS-Na> BX> Terwet 1004等)、复合润湿剂(Mo rwet EFff)中一种或多种；填料如娃藻土、高岭土、轻钙、滑石粉、白炭黑、凹凸棒土、陶土、硫酸铵、尿素、蔗糖、葡萄糖、玉米淀粉、硫酸钠、多聚磷酸钠等ー种或多种。 [0012] The wettable powders, additives that may be used are: a dispersant such as polycarboxylates (TERSPERSE 2700, T36, GY-D06, etc.), lignin cross bisphosphonates (Ufoxane 3A, Borresperse NA, Borresperse CA -SA, etc.), naphthalene and alkyl naphthalene sulfonate formaldehyde condensates (NNO, MF, Morwet D-425, Tamol NN, TERSPERSE2020 etc.), opened powder BX (Ni-butyl naphthalene sulfonate), EO- PO block polyether, alkylphenol ko ene ether phosphate, alkylphenol ether formaldehyde condensates ko ene sulphate (S0PA), in ー or more; wetting agents such as sulfates Class (K-12), sulfonate (ABS-Na> BX> Terwet 1004, etc.), composite wetting agent (Mo rwet EFff) one or more; fillers such as baby diatomaceous earth, kaolin, light calcium, talc, silica, attapulgite clay, ammonium sulfate, urea, sucrose, dextrose, corn starch, sodium sulfate, sodium polyphosphate and other ー or more.

[0013] 对悬浮剂，可使用的助剂有:分散剂如聚羧酸盐、木质素磺酸盐、烷基萘磺酸盐、TERSPERSE 2020 (美国亨斯迈公司HUNTSMAN出品，烷基萘磺酸盐类)中ー种或多种；乳化剤如农乳700# (通用名:烷基酚甲醛树脂聚氧こ烯醚)、斯盘-60# (通用名:山梨醇酐单硬脂酸酷)、吐温-60# (通用名:失水山梨醇单硬脂酸酯聚氧こ烯醚)、农乳1601# (通用名:苯こ基苯酚聚氧こ烯聚氧丙烯醚)、TERSPERSE 4894 (美国亨斯迈公司出品)中的ー种或多种；润湿剂如烷基酚聚氧こ烯基醚甲醛缩合物硫酸盐、烷基酚聚氧こ烯基醚磷酸酯、苯こ基酚聚氧こ烯基醚磷酸酷、烷基硫酸盐、烷基磺酸盐、萘磺酸盐、TERSPERSE 2500 (美国亨斯迈公司出品)中ー种或多种；增稠剂如黄原胶、聚こ烯醇、膨润土、硅酸镁铝中ー种或多种；防腐剤如甲醛、苯甲酸、苯甲酸钠中ー种或多种；消泡剂如有机硅类消泡剂；防冻剂如こニ醇、丙ニ醇、甘油、尿素、无机盐类如氯化钠中ー种或多种，水为去离子水。 [0013] The suspensions, additives that may be used are: a dispersant such as polycarboxylates, lignin sulfonate, alkyl naphthalene sulfonate, TERSPERSE 2020 (US Huntsman HUNTSMAN produced, alkyl naphthalene sulfonate bisphosphonates) in ー or more; emulsifying Ji such as dairy farming and # 700 (generic name: alkyl phenol formaldehyde resin polyoxyethylene ko ene ether), Andean -60 # (generic name: Cool Sorbitan monostearate ), Tween -60 # (generic name: sorbitan monostearate polyoxyethylene ko ene ether), dairy farming 1601 # (generic name: Benzene ko ko ene phenol polyoxyethylene polyoxypropylene ether), TERSPERSE 4894 (Huntsman Corp.) in ー or more; wetting agents such as alkylphenol formaldehyde condensates ko vinyl ether sulfates, alkylphenol ether phosphates ko ene, benzene ko phenol polyoxyethylene ether phosphoric acid ko ene cool, alkyl sulfates, alkyl sulfonate, naphthalene sulfonate, TERSPERSE 2500 (Huntsman Corp.) in ー or more; thickening agents such as xanthan plastic, polyethylene ko alcohol, bentonite, magnesium aluminum ー or more; preservative Ji such as formaldehyde, benzoic acid, sodium benzoate ー or more; defoamers such as silicone defoamers; antifreeze alcohols such as ko ni, ni propyl alcohol, glycerol, urea, inorganic salts such as sodium chloride ー or more, the water is deionized water.

[0014] 对于乳油来说，可使用的助剂有:乳化剂如十二烷基苯磺酸钙(农乳500#)、农乳700#、农乳2201#、斯盘-60#、乳化剂T-60 (通用名:失水山梨醇单硬脂酸酯聚氧こ烯醚)、TX-10 (通用名:辛基酚聚氧こ烯(10)醚)、农乳1601#、农乳600#、农乳400#中ー种或多种；溶剂如ニ甲苯、溶剂油(S-150、S-180、S-200)、甲苯、生物柴油、甲酯化植物油；助溶剂:こ酸こ酷、甲醇、ニ甲基甲酰胺、环己酮、丙酮、甲こ酮中ー种或多种。 [0014] For the EC, the aid may be used are: emulsifiers such as calcium dodecylbenzenesulfonate (Nongru 500 #), # 700 dairy farming, dairy farming 2201 #, Span -60 #, emulsification agent T-60 (generic name: sorbitan monostearate polyoxyethylene ko ene ether), TX-10 (generic name: octylphenol polyoxyethylene ko ene (10) ether), 1601 # dairy farming, agriculture Milk # 600, # 400 in dairy farming ー or more; Ni solvent such as toluene, solvent oil (S-150, S-180, S-200), toluene, biodiesel, vegetable oil methyl ester; cosolvent: ko Cool ko acid, methanol, ni dimethylformamide, cyclohexanone, acetone, methyl ketone ー ko or more.

[0015] 对微乳剂，可使用的助剂有:乳化剂如十二烷基苯磺酸钙(农乳500#)、农乳700#、农乳2201#、斯盘-60#、吐温-60#、TX-10、农乳1601#、农乳600#、农乳400#中ー种或多种；助乳化剂如甲醇、异丙醇、正丁醇、こ醇中ー种或多种；溶剂如环己酮、N-甲基吡咯烷酮、ニ甲苯、甲苯、溶剂油(牌号:S-150、S-180、S-200) ー种或多种；水为去离子水。 [0015] The micro-emulsion, additives that may be used include: emulsifiers such as calcium dodecylbenzenesulfonate (Nongru 500 #), # 700 dairy farming, dairy farming 2201 #, Span -60 #, Twain -60 #, TX-10, 1601 # dairy farming, dairy farming 600 #, 400 # in dairy farming ー or more; co-emulsifier such as methanol, isopropanol, n-butanol, an alcohol ー ko species or species; solvents such as cyclohexanone, N- methylpyrrolidone, Ni, toluene, solvent oil (grade: S-150, S-180, S-200) ー or more; water is deionized water.

[0016] 本发明组分合理，杀虫效果好，用药成本低，且其活性和杀虫效果不是各组分活性的简单叠加，而是有显著的增效作用，对作物安全性好，符合农药制剂的安全性要求。 [0016] The present invention component reasonable, good insecticidal effect, low administration costs, and its insecticidal activity and the effect is not the simple sum of the components of each activity, but a significant synergistic effect on crop safety, in line with pesticide formulations security requirements. 本发明对危害农作物的蚜虫、蝽象有较高的杀虫活性。 The present invention is to damage crops aphids, bugs like there is a high insecticidal activity.

具体实施方式 DETAILED DESCRIPTION

[0017] 为了防治农业生产上的蚜虫，发明人以环氧虫啉分别与联苯菊酷、高效氯氟氰菊酯进行了相互复配的增效研究。 [0017] In order to control aphids on agricultural production, the inventors respectively Bifenthrin epoxy insect morpholine, cyhalothrin conducted research complex of mutually reinforcing. 试验采用苹果黄蚜为测试对象，具体方法为: Test uses aphid test object, specific methods are:

苹果黄姆(Aphis pomi DeGeer),又名绣线菊姆,属同翅目，姆科。 Apple Huang Mu (Aphis pomi DeGeer), also known as Meadowsweet Farm, Homoptera, Muke. 将原药配制成需要的试验药剂，试验方法參考《中华人民共和国农业行业标准NY/T1154.6-2006》。 Original drug formulated to require drug tests, test methods refer to "People's Republic of China agricultural industry standards NY / T1154.6-2006". 首先将单剂及各混配药剂设置5个不同浓度梯度(蚜虫死亡率在5%~90%的范围内按等比级数设定)。 First, a single agent and each compounding agents set up five different concentrations (Aphid mortality in the range of 5% to 90% set by geometric progression). 试虫为采自田间的蚜虫，在实验室挑选均匀一致的蚜虫，放入带有叶片的培养皿内，每皿40头虫子,每处理4个培养皿，重复3次，用potter喷雾塔在50PSI压カ下喷雾，每次喷ー个皿，每皿喷药液3ml，然后将处理过的培养皿放入12H/12H光照培养箱内培养，72小时检查死虫数,计算死亡率。 The insects as aphids collected from the field, in the laboratory selected uniform aphid, placed in a petri dish with blades, 40 insects per dish, each dish handle 4, repeated three times, with potter spray tower 50PSI grades under pressure spray, spray each ー a dish, each dish spraying liquid 3ml, then placed in petri dishes treated 12H / 12H light incubator for 72 hours to check the number of dead insects, mortality was calculated. 空白对照喷等量清水。 Blank spray the same amount of water. 通过死亡率的机率值和系列浓度的对数值之间的线性回归分析，求出各药剂的LC5tl值，用孙云沛法计算混剂的共毒系数(CTC)，以此来评价供试药剂对试虫的活性。 By mortality probability values ​​and a series of concentrations of the linear regression analysis between the values ​​obtained LC5tl value of each agent, calculated mixture by co-toxicity coefficient (CTC) by 孙云沛 method, in order to evaluate the test agents on trial activity of insects.

[0018] 复配制剂的共毒系数(CTC)≥120表现为增效作用；CTC≤80表现为拮抗作用；80 < CTC < 120表现为相加作用。 [0018] Mixture of co-toxicity coefficient (CTC) ≥120 showed synergism; CTC≤80 were antagonistic; 80 <CTC <120 showed an additive effect.

表1-1环氧虫啉与联苯菊酯组合对苹栗黄蚜的室内毒カ测定 Table 1-1 epoxy insect morpholine and bifenthrin combination of apple aphid chestnut Toxicity grades determination

[0019] 室内毒力測定结果表明:环氧虫啉和联苯菊酯、高效氯氟氰菊酯以重量比为1:10~20:1混用对苹果黄蚜有较好的毒力，均有显著的增效作用。 [0019] Toxicity test showed that: Epoxy insect morpholine and bifenthrin, cyhalothrin weight ratio of 1:10 to 20: 1 mix of apple aphid better virulence are There are significant synergies.

[0020] 为了防治农业生产上的各类蝽象，发明人以环氧虫啉分别与联苯菊酷、高效氯氟氰菊酯进行了相互复配的增效研究。 [0020] In order to combat all kinds of bugs like agricultural production, the inventors respectively Bifenthrin epoxy insect morpholine, cyhalothrin conducted research complex of mutually reinforcing. 试验采用棉花绿盲蝽为测试对象，具体方法为: Test using cotton lucorum test object, specific methods are:

绿盲蜷，学名Apolygus lucorum Meyer-Diir,属半翅目盲蜷科。 Lygus curled, scientific name Apolygus lucorum Meyer-Diir, it is a semi-blind wing curled Section. 将原药配制成需要的试验药剂。 Original test drug formulated as pharmaceutical needs. 首先将单剂及各混配药剂设置5个不同浓度梯度(在预备试验结果的基础上，绿盲蝽死亡率在5%~90%的范围内按等比级数设定)。 First, a single agent and each compounding agents set up five different concentrations (based on preliminary test results, lucorum mortality rate in the range of 5% to 90% set by geometric progression). 试虫为棉田采集绿盲蝽成虫,在室内豆角上饲养，至下一代若虫发育到3龄供试。 The insects to cotton fields collection lucorum adult, feeding on the interior beans, to the next generation of development to third instar nymphs of the test. 将新鮮大小一致的棉花叶片在药液中浸溃30 s后，于室温条件下自然晾干，而后放入塑料盒(直径8 cm，高5 cm)中，接入活泼健康、大小一致的3龄幼虫，15头/盒，用带有小孔的盒盖盖好。 After the fresh leaves of the same size of cotton dipped in liquid collapse 30 s, dry naturally at room temperature, then placed in a plastic box (diameter 8 cm, height 5 cm), and access to active and healthy, consistent with the size of 3 instar larvae, 15 / box, with a lid with a hole in the cover. 另设空白对照，重复3次。 Another blank control, repeated three times. 置温度为26~28で、相対湿度为70%左右的光照培养箱内饲养观察。 Set temperature of 26 to 28 で relative humidity within Dui about 70% of light incubator rearing. 48小时检查试虫的死亡情况。 48 hours to check the test insect mortality. 通过死亡率的机率值和系列浓度的对数值之间的线性回归分析，求出各药剂的LC5tl值，用孙云沛法计算混剂的共毒系数(CTC)，以此来评价供试药剂对试虫的活性。 By mortality probability values ​​and a series of concentrations of the linear regression analysis between the values ​​obtained LC5tl value of each agent, calculated mixture by co-toxicity coefficient (CTC) by 孙云沛 method, in order to evaluate the test agents on trial activity of insects.

[0021] 复配制剂的共毒系数(CTC)≥120表现为增效作用； CTC≤80表现为拮抗作用；80 < CTC < 120表现为相加作用。 [0021] Mixture of co-toxicity coefficient (CTC) ≥120 showed synergism; CTC≤80 were antagonistic; 80 <CTC <120 showed an additive effect.

[0022] 室内毒力測定结果表明:环氧虫啉和联苯菊酯、高效氯氟氰菊酯以重量比为1:10-20:1混用对绿盲蝽有较好的毒力，均有增效作用。 [0022] Toxicity test showed that: Epoxy insect morpholine and bifenthrin, cyhalothrin in a weight ratio of 1: 10-20: 1 mix of lucorum better virulence are There are synergies.

[0023] 下面结合实施例对本发明作进ー步说明。 [0023] The following combination of embodiments of the present invention will be described further into ー.

[0024] 制剂实施例1 [0024] Formulation Example 1

称取10%环氧虫啉、10%联苯菊酷、3% GY-D06 (聚羧酸盐)、3%木质素磺酸钠、1%TERSPERSE2020、1% K-12 (十二烷基硫酸钠)、1%PVA (分子量2000)、10%聚こ烯吡咯烷酮、高岭土加至100%重量份。 Weigh 10% of ethylene insects morpholine, Bifenthrin 10%, 3% GY-D06 (polycarboxylates), 3% of sodium lignosulfonate, 1% TERSPERSE2020,1% K-12 (sodium dodecyl sodium sulfate), 1% PVA (molecular weight 2000), 10% polyethylene ko polyvinylpyrrolidone, kaolin added to 100% by weight. 上述原料经常规制取水分散粒剂的方法即混合、超微气流粉碎、混合、造粒步骤制取20%环氧虫啉•联苯菊酯水分散粒剂。 The raw material manufactured by conventional water dispersible granules method that is mixed with ultrafine jet milling, mixing, granulating step preparation of 20% ethylene insect morpholine • bifenthrin water dispersible granules.

[0025] 制剂实施例2称取60%环氧虫啉、20%高效氯氟氰菊酷、2% TERSPERSE 2700 (聚羧酸盐，美国亨斯迈公司出品)、2%扩散剂NNO (烷基萘磺酸盐甲醛缩合物)、2%拉开粉BX (ニ丁基萘磺酸钠)、2%K-12、2%硅藻土、1%尿素、高岭土加至100%重量份。 [0025] Formulation Example 2 weighed 60% ethylene insect morpholine, 20% cyhalothrin chrysanthemum cool, 2% TERSPERSE 2700 (polycarboxylate, Huntsman Corp.), 2% diffusion agent NNO (alkyl naphthalene sulfonate formaldehyde condensates), 2% Nekal BX (ni-butyl naphthalene sulfonate), 2% K-12,2% diatomaceous earth, 1% urea, kaolin added to 100% by weight. 上述原料经常规制取水分散粒剂的方法即混合、超微气流粉碎、混合、造粒步骤制取80%环氧虫啉•高效氯氟氰菊酯水分散粒剂。 The raw material manufactured by conventional water dispersible granules method that is mixed with ultrafine jet milling, mixing, granulating step preparation of 80% ethylene insect morpholine • cyhalothrin water dispersible granules.

[0026] 制剂实施例3 [0026] Formulation Example 3

称取60%环氧虫啉、3%联苯菊酷、6%木质素磺酸I11KUfoxane 3A)、3%烷基萘磺酸盐甲醛缩合物(Tamol NN)、1%十二烷基硫酸钠、5%白炭黑、高岭土加足至100%的重量份。 Weigh 60% of ethylene insect morpholine, Bifenthrin 3%, 6% lignosulfonate I11KUfoxane 3A), 3% alkylnaphthalene sulfonate formaldehyde condensate (Tamol NN), 1% sodium dodecyl sulfate 5% silica, kaolin add a little to 100% by weight. 上述原料经混合、超微气流粉碎、混合エ艺步骤制备得63%环氧虫啉•联苯菊酯可湿性粉剂。 The raw material has been mixed ultrafine jet milling, mixing EVAL process steps preparation was 63% ethylene insect morpholine • bifenthrin wettable powder.

[0027] 制剂实施例4 [0027] Formulation Example 4

称取5%环氧虫啉、50%高效氯氟氰菊酷、6%木质素磺酸钙、4%烷基萘磺酸盐甲醛缩合物(Morwet D_425)、l.5%十二烷基硫酸钠、12%白炭黑、轻钙加足至100%的重量份。 Weigh 5% of epoxy insect morpholine, 50% cyhalothrin chrysanthemum cool, 6% calcium lignin sulfonate, 4% alkyl naphthalene sulfonate formaldehyde condensate (Morwet D_425), l.5% sodium dodecyl sodium, 12% silica, calcium and light enough to 100% by weight. 上述原料经混合、超微气流粉碎、混合エ艺步骤制备得55%环氧虫啉•高效氯氟氰菊酯可湿性粉剂。 The raw material has been mixed ultrafine jet milling, mixing EVAL process steps preparation was 55% ethylene insect morpholine • cyhalothrin wettable powder.

[0028] 制剂实施例5 [0028] Formulation Example 5

称取20% 环氧虫啉、4% 联苯菊酷、3%TERSPERSE 4894、1%TERSPERSE 2500,0.3% 黄原胶、5%丙ニ醇、0.5%苯甲酸、0.5%有机硅消泡剂(商品名:s-29南京四新应用化学品公司出品)、去离子水加至100%重量份。 Weigh 20% of ethylene insect morpholine, Bifenthrin 4%, 3% TERSPERSE 4894,1% TERSPERSE 2500,0.3% xanthan gum, 5% Ni propyl alcohol, 0.5% acid, 0.5% silicone defoamer (trade name: s-29 Nanjing four new chemicals should Corp.), deionized water to 100% by weight. 上述原料经混合，高速剪切分散30min，用砂磨机砂磨后制得24%环氧虫啉•联苯菊酯悬浮剂。 The raw material has been mixed, high-speed shearing dispersion 30min, after sanding with a sand mill to obtain 24% of ethylene insect morpholine • bifenthrin suspension.

`[0029] 制剂实施例6 `[0029] Formulation Example 6

称取10%环氧虫啉、20%高效氯氟氰菊酷、1%TERSPERSE 2020 (美国亨斯迈公司出品)、3%农乳700#、3%农乳1601#、2%TERSPERSE 2500,0.3%黄原胶、5%丙ニ醇、0.5%苯甲酸、0.5%有机硅消泡剂(商品名:s-29南京四新应用化学品公司出品)、去离子水加至100%重量份。 Weigh 10% ethylene insect morpholine, 20% cyhalothrin chrysanthemum cool, 1% TERSPERSE 2020 (Huntsman Corp.), 3% Nongru 700 #, 3% Nongru 1601 #, 2% TERSPERSE 2500, 0.3% xanthan gum, 5% propyl alcohol Ni, 0.5% benzoic acid, 0.5% silicone defoamer (trade name: s-29 Nanjing four new chemicals should Corp.), deionized water to 100% by weight . 上述原料经混合，高速剪切分散30min，用砂磨机砂磨后制得30%环氧虫啉•高效氯氟氰菊酯悬浮剂。 The raw material has been mixed, high-speed shearing dispersion 30min, after sanding with a sand mill to obtain 30% of ethylene insect morpholine • cyhalothrin suspensions.

[0030] 制剂实施例7 [0030] Formulation Example 7

称取5%环氧虫啉、25%联苯菊酷、4%农乳500#、2%农乳600#、3%农乳2201#、15% ニ甲基甲酰胺、溶剂油S-180加至100%重量份。 Weigh 5% of epoxy insect morpholine, Bifenthrin 25%, 4% Nongru 500 #, 600 # 2% dairy farming, dairy farming 2201 # 3%, 15% Ni dimethylformamide, solvent oil S-180 to 100% by weight. 上述原料经混合，搅拌溶解完全后制得30%环氧虫啉•联苯菊酯乳油。 The raw material has been mixed, stirring dissolved completely to obtain 30% of ethylene insect morpholine • bifenthrin EC.

[0031] 制剂实施例8 [0031] Formulation Example 8

称取7.5%环氧虫啉、2.5%高效氯氟氰菊酷、5%农乳500#、3% TX_10、4%农乳1601#、20%丙酮、ニ甲苯加至100%重量份。 Weigh 7.5% ethylene insect morpholine, 2.5% cyhalothrin chrysanthemum cool, 5% Nongru 500 #, 3% TX_10,4% Nongru 1601 #, 20% acetone, toluene ni to 100% by weight. 上述原料经混合，搅拌溶解完全后制得10%环氧虫啉•高效氯氟氰菊酯乳油。 The raw material has been mixed, stirring dissolved completely to obtain 10% of ethylene insect morpholine • cyhalothrin EC.

[0032] 制剂实施例9 [0032] Formulation Example 9

称取2%环氧虫啉、1%联苯菊酷、4%TX-10、5%农乳700#、6%农乳500#、4%农乳1601#、10%环己酮、5%N-甲基吡咯烷酮、5%正丁醇，经溶解完全并混合均匀，去离子水加至100%重量份，搅拌后制得3%环氧虫啉•联苯菊酯微乳剂。 Weigh 2% epoxy insects morpholine, 1% Bifenthrin, 4% TX-10,5% Nongru 700 #, 500 # 6% of dairy farming, dairy farming 1601 # 4%, 10% of cyclohexanone, 5 % N- methylpyrrolidone, 5% n-butanol, and completely dissolved by mixing, deionized water to 100% by weight, and stirred to obtain an epoxy worm 3% morpholine • bifenthrin microemulsion.

[0033] 制剂实施例10 [0033] Formulation Example 10

称取5%环氧虫啉、15%高效氯氟氰菊酷、5%农乳700#、3%农乳500#、6%农乳600#、5%ニ甲苯、20%环已酮、5%こ醇，经溶解完全并混合均匀，去离子水加至100%重量份，搅拌后制得20%环氧虫啉•高效氯氟氰菊酯微乳剂。 Weigh 5% of epoxy insect morpholine, 15% cyhalothrin chrysanthemum cool, 5% Nongru 700 #, 500 # 3 percent dairy farming, dairy farming 600 # 6%, 5% Ni toluene, 20% of cyclohexanone, 5% ko alcohol, by dissolving completely and uniformly mixed with deionized water to 100% by weight, and stirred to obtain 20% of ethylene insect morpholine • cyhalothrin microemulsion.

[0034] 生物实施例1:防治棉盲蝽、棉蚜田间试验 1 [0034] Biological Examples: Combat cotton plant bugs, cotton aphid field trials

发明人于2013年7月在陕西省渭南市临渭区做了制剂实例I (20%环氧虫啉•联苯菊酷水分散粒剂)、制剂实施例8 (10%环氧虫啉•高效氯氟氰菊酯乳油)防治棉盲蝽、棉蚜田间药效试验，试验參照《农药田间药效试验准则HY/T 1464.3-2007杀虫剂防治棉盲蝽》和《农药田间药效试验准则(ニ)GB/T 17980.75-2004杀虫剂防治棉花蚜虫》。 Inventors in July 2013 in Weinan City, Shaanxi Province Linwei done Formulation Example I (20% ethylene insect morpholine • Bifenthrin water dispersible granules), Formulation Example 8 (10% ethylene insect morpholine • cyhalothrin EC) Prevention cotton plant bugs, cotton aphid field efficacy trials, test refer to "Guidelines for the field efficacy trials HY / T 1464.3-2007 insecticides against cotton plant bugs" and "efficacy evaluation of pesticides Criterion (ni) GB / T 17980.75-2004 insecticides against cotton aphid. " 试验作物为棉花，防治对象为棉花绿盲蝽、棉蚜。 Test crops are cotton, cotton Control Target lucorum, cotton aphid. 试验棉花田土壤为粘土，肥力中等，各小区的栽培条件、水肥管理均匀一致。 Test cotton field soil is clay, medium fertility, cultivation conditions for each cell, the uniform water and fertilizer management. 两种试验对象均发生较重。 Two test subjects were heavier occur. 7月20日施药，用药液量为60kg/667m2，采用手动喷雾器均匀喷施，要求各小区棉花叶片正反面、边尖、花蕾均匀着药。 July 20 application, with the liquid volume of 60kg / 667m2, with manual sprayer evenly spraying, requiring each cell cotton leaves front and back side of the tip, bud even the drug. 试验药剂及剂量详见表3。 Experimental drug and dose are shown in Table 3. 另设空白对照，每处理4次重复，每小区面积50 Hf，共40个小区，随机区组排列。 Another blank control, with four replicates per treatment, each plot area 50 Hf, a total of 40 quarters, randomized block.

[0035] 棉盲蝽调查方法: [0035] Cotton Lygus Survey Methods:

施药前调查基数，施药后1、3、7天分别调查残虫数。 Spraying before the survey base, 1,3,7 days after spraying insect residues, respectively, the number of investigations. 每小区采用对角线5点取样，每点连续查10 —15株棉花，并挂牌标记，调查并记录每株棉花上棉盲蝽的成、若虫数量。 Each cell sample using diagonal 5:00, 10-15 continuous search cotton plants every point, and listed markers, survey and record each plant cotton into cotton plant bug nymphs number. 根据棉盲蝽的成、若虫昼夜节律，宜选择虫体不活跃时进行调查。 According to the cotton plant bug nymphs circadian rhythm, an investigation should be chosen when the parasite is not active.

[0036] 棉蚜调查方法: [0036] cotton aphid survey methods:

对角线五点取样，每点固定4株，每株固定上、中、下3片叶，共固定调查20株60片叶，调查记录活蚜虫数。 Diagonal five-point sampling, fixed 4 per point per plant fixed, middle and lower leaves were fixed survey 20 60 leaves, the survey recorded live aphids. 药前调查虫ロ基数，药后1、3、7天各调查I次小区的残存蚜虫数，依据药前虫ロ基数和药后各天的残虫量计算校正防效。 Prodrug investigation insect ro base, 1,3,7 days after the drug each time I survey the number of cells remaining aphids, the days of residual insect control effect after correction calculation based on a prodrug worm ro base and medicine.

[0037] 防治棉盲蝽、棉蚜药效按下面的公式计算: [0037] Prevention cotton plant bugs, cotton aphid efficacy according to the following formula:

防治效果(％)=[ 1一(对照区药前虫数X处理区药后虫数)/(对照区药后虫数X处理区药前虫数)]X 100。 Control effect (%) = [1 - (number of former drug control area X number of insects treated area after injection worm) / (number of insect drug control area after the number of insects before drug treatment zone X)] X 100.

[0038] 毎次调查药效时同时观察各处理区对棉花叶片、花蕾及其它害虫的影响。 [0038] while observing the effect of each treatment every area of ​​cotton leaves, buds and other pests when surveys efficacy.

[0039] 试验结果表明，20%环氧虫啉•联苯菊酯水分散粒剂3000倍、3500倍、4000倍，10% [0039] The results showed that 20% of ethylene insect morpholine • bifenthrin WDG 3000 times, 3500 times, 4000 times, 10%

环氧虫啉•高效氯氟氰菊酯乳油2000倍、2500倍、3000倍对棉花绿盲蝽、棉蚜有较显著的防治效果，明显优于10%环氧虫啉悬浮剂1000倍、10%联苯菊酯乳油2000倍、2.5%高效氯氟氰菊酯1000倍的防治效果(表3)。 Epoxy insect morpholino • cyhalothrin EC 2000 times, 2500 times, 3000 times lucorum cotton, cotton aphid more significant control effect, obviously better than 10% ethylene insect morpholine SC 1000, 10 % bifenthrin EC 2000 times, 2.5% cyhalothrin 1000 times control effects (Table 3).

安全性调查，试验期间观察，所有供试药剂对棉花生长安全，无药害现象发生。 Security Survey, observed during the test, all the tested pesticides on cotton growth and security, no injury occurred.

[0040] 试验结果表明，环氧虫啉与联苯菊酯、高效氯氟氰菊酯混配后，明显提高了对棉盲蝽、棉蚜的防治效果，在这两种害虫同时发生时，一次施药达到兼治，降低了用药量，減少了用药次数及用药成本，对棉花生长安全，是防治棉盲蝽、棉蚜的理想药剂。 [0040] The results showed that the epoxy insect morpholine and bifenthrin, cyhalothrin mixed, the significantly increased cotton plant bug, cotton aphid control effect, in which the two pests occur simultaneously, a pesticide to rid reached, reducing the dosage, reducing the number of drugs and medication costs of cotton growing security, prevention and treatment of the cotton plant bug, the ideal drug Cotton.

[0041] 从以上实施例中可见，第一活性成分环氧虫啉与第二活性成分联苯菊酯或高效氯氟氰菊酯组合复配，可制成水分散粒剂、可湿性粉剂、悬浮剂、乳油或微乳剂剂型，对危害农作物的蚜虫、蝽象有显著的防治效果，用药量少、防治效果高等优点，节约了用药成本和用药量，且对作物安全性良好，因此生产上有广泛的应用前景。 [0041] From the above examples can be seen, the first active ingredient epoxy insect morpholine and a second active ingredient bifenthrin or cyhalothrin complex combinations can be made water dispersible granules, wettable powders, suspensions, creams or microemulsion formulation of aphids crops, stinkbug have significant control effect, less medication, control effect advantages, saving the cost of medication and dosage, and safety of the crop is good, so the production on There are a wide range of applications.

[0042] 综上所述，本发明的组合物是采用两种活性成分复配方案，其活性和杀虫效果不是各组分活性的简单叠加，与现有的単一制剂相比，除具有显著的杀虫效果外，而且有显著的增效作用，对作物安全性好，符合`农药制剂的安全性要求。 [0042] In summary, the compositions of the present invention is the use of the two active ingredients mixed solution, the simple sum of the activity of each component and the insecticidal effect is not active, as compared with a conventional radiolabeling agents, in addition to having It marked insecticidal effect, but a significant synergistic effect on crop safety, in line with `pesticide formulations security requirements.