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Molecular mechanisms of mitochondrial homeostasis regulation in neurons and possible therapeutic approaches for Alzheimer's disease

ScienceDirect.com
Recent studies demonstrate that imbalance of mitochondrial homeostasis is a driver in Aβ accumulation, which can lead to the occurrence and deterioration of...
2 months ago

Efficacy and safety of catheter ablation for atrial fibrillation in patients with heart failure with preserved ejection fraction: a systematic review and meta-analysis

Frontiers
BackgroundCatheter ablation (CA) effectively treats atrial fibrillation (AF) in heart failure (HF) with reduced ejection fraction (HFrEF),...
4 months ago

The Intersection of cerebral cholesterol metabolism and Alzheimer's disease: Mechanisms and therapeutic prospects

ScienceDirect.com
We reviewed recent research on the interplay between cerebral cholesterol homeostasis and AD, highlighting its significance in AD pathogenesis.
6 months ago

Strategies for mitigating challenges associated with trace organic compound removal by high-retention membrane bioreactors (HR-MBRs) | npj Clean Water

Nature
Due to the limitations of conventional ultrafiltration/microfiltration-based membrane bioreactors (UF/MF-MBRs) in removing trace organic...
8 months ago

Long-Acting Antibacterial Hydrogels Constructed by Interface-Induced Directional Assembly

ACS Publications
Self-assembled supermolecular hydrogels of therapeutic agents without structural modification are of great significance in biomedical...
5 months ago

Engineering properties of Cassia tora L. seeds and meal as a function of moisture content

Nature
Engineering properties are of great importance for Cassia tora L. seeds in aspects of harvesting, handling mechanical design and product processing.
30 months ago

Expression of Phosphofructokinase Is Not Sufficient to Enable Embden-Meyerhof-Parnas Glycolysis in Zymomonas mobilis ZM4

Frontiers
Zymomonas mobilis is a bacterium that produces ethanol from glucose at up to 97% of theoretical efficiency on a carbon basis.
62 months ago

Emerging tools and best practices for studying gut microbial community metabolism

Nature
The human gut microbiome vastly extends the set of metabolic reactions catalysed by our own cells, with far-reaching consequences for host...
5 months ago

Axonal generation of amyloid-β from palmitoylated APP in mitochondria-associated endoplasmic reticulum membranes

ScienceDirect.com
We develop a microfluidic device and use it to show that MAM levels alter Aβ generation specifically in neuronal processes and axons, but not in cell bodies.
42 months ago

Aortic Fistulas: Pathophysiologic Features, Imaging Findings, and Diagnostic Pitfalls

Radiological Society of North America | RSNA
Fistulas between the aorta and surrounding organs are extremely rare but can be fatal if they are not identified and treated promptly.
40 months ago